On October 19, 2025, an exciting NFL matchup is set between the New York Giants and the Denver Broncos at Empower Field at Mile High in Denver, starting at 4:05 PM. The Giants, currently 4th in their division and 15th in their conference with a 1-3 record, have a challenging road as they’ve managed 73 points for and allowed 101 points against, resulting in a -28 net point difference. In contrast, the Broncos are slightly ahead with a 1-2 record, ranked 3rd in their division and 9th in the conference, scoring 68 points while conceding 64, a net positive of 4 points.

Last game performances saw the Giants struggle at home against Cincinnati, losing 17-7, despite gaining 119 rushing yards and 190 yards through the air. The Broncos, playing at home, were also handed a defeat by the Chargers with a close scoreline of 23-16. They accumulated 110 rushing yards and 206 passing yards. Quarterback Daniel Jones of the Giants had a tough day with 205 passing yards, no touchdowns, and a 57.47 passer rating. On the opposite field, Bo Nix of the Broncos impressed with 216 passing yards and two touchdowns, achieving an 84.91 passer rating.

Looking at this week’s game, both teams will lean heavily on their quarterbacks; Daniel Jones for the Giants and Bo Nix for the Broncos, who will both aim to improve their performances from the last outing.

Odds have been set favoring the home team: the Denver Broncos have a point spread of -8.00, suggesting confidence in their ability to conquer the Giants, who stand at an 8.60 point spread. The game’s over/under is fixed at 45.60, pointing towards expectations of a moderately high-scoring match. For direct wins, the odds are clearly leaning towards Denver with a moneyline of -381, while the Giants are underdogs at +300. These odds suggest an anticipated Denver victory, but in football, outcomes can be unpredictable, highlighting the thrills this game could potentially offer to viewers and bettors alike.