On November 2, 2025, a compelling NFL clash is scheduled as the San Francisco 49ers visit the New York Giants at MetLife Stadium in East Rutherford. The kickoff is set for 1:00 PM.

The San Francisco 49ers have made a strong start to the season, leading their division and holding the second spot in their conference with a 3-1-0 record, demonstrating a .750 winning percentage. They have managed to score 80 points while conceding 75, resulting in a net difference of +5 points.

On the other hand, the New York Giants have had a challenging start, positioned 4th in their division and 15th in their conference, reflecting a 1-3-0 record with a .250 winning percentage. Their offensive output stands at 73 points against 101 points conceded, leading to a net difference of -28 points.

In their recent games, the 49ers suffered a 18-28 defeat to Kansas City at Levi’s Stadium, recording 19 first downs and accumulating 101 rushing yards and 209 passing yards. Conversely, the Giants faced a tough 3-28 loss against Philadelphia at home, managing 10 first downs with 76 rushing yards and only 43 passing yards.

Quarterback performance will be a key factor again as Brock Purdy, despite last week’s challenging game where he posted 212 passing yards with a passer rating of 36.69, and Daniel Jones of the Giants, who threw for 99 yards with a higher passer rating of 77.28, prepare to lead their teams.

Betting Analysis:
For those interested in the betting aspect, the odds forecast a tight contest. The point spread is set at -3.50 in favor of the visiting 49ers, reflecting their stronger season performance thus far. The Giants are at +3.50, indicating their underdog status at home. The over/under for the game is pegged at 44.70, suggesting expectations of a moderately high-scoring game. For outright wins, the money line favors the 49ers at -193, whereas the Giants are positioned at +161, highlighting the betting community’s anticipation of a 49ers win but acknowledging potential upsets. Monitor these odds for strategic bets at betMississippisports.com.

This matchup promises to deliver thrilling football action, spotlighting key performances and strategic plays pivotal for the season trajectories of both teams.